Thursday, June 12, 2008

Can PEP reduce mother-to-child transmission of HIV?

Recent studies may offer hope to many HIV+ mothers with newborns. Effective strategies are urgently needed to reduce mother-to-child transmission of human immunodeficiency virus through breast-feeding. Post-Exposure Prophylaxis is using antiretroviral drugs to stop the transmission. Studies now may offer hope using single-dose Nevirapine plus 1 week of Zidovudine or extended Nevirapine or extended Zidovudine until the age of 14 weeks. This may significantly reduce postnatal HIV infection in 9-month-old infants. Or will HAART be a concern with the onset of side effects? Should we place the already vulnerable newborn at more risk? What are your thoughts?

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